The Barna Lab seeks to address how the living blueprints of developing organisms are built. We seek to understand the control of gene expression. A major direction in the lab is to understand how such long-range interactions occur, how they achieve target specificity, and how they may be reprogrammed by alterations to the genome sequence. Our laboratory is interested in the .

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We study the primary cilium, a surface-exposed organelle required for vision, olfaction and developmental signaling and whose dysfunction leads to. 8203; obesity, skeletal malformations and kidney cysts. To decode the fundamental principles of ciliary trafficking and to understand. How trafficking shapes signaling at the primary cilium, we leverage. A broad expertise in biochemistry, proteomics, cell biology and in vitro reconstitution.